ReSyn Mag Beads
ReSyn Biosciences currently offers a portfolio of innovative magnetic microparticle products, MagReSyn®, designed to specifically address the requirements of bioseparation, mass spectrometry and proteomics sample preparation. The products aim to address key limitations in R&D workflows, including reproducibility and low throughput, by developing automated workflows, and enabling clinical mass spectrometry applications.
MagReSyn technology has innovated the development of new miniaturized, high throughput technologies for bioseparation, diagnostics, DNA sequencing, flow cytometry, drug discovery, proteomics and genomics are in many instances reliant on attachment of functional biological molecules to a microsphere support. Based on the vast array of life sciences, applications include: capture reagents for immunoassay (fluorescence, enzyme linked etc); surfaces for immunoprecipitation; diagnostic assays; fluorescence microscopy; flow/imaging cytometry; magnetic cell separation; molecular diagnostics; agglutination tests; nucleic acid separation and protein separation among others.
Technical advantages of ReSyn for bioseparation:
- High biomolecule binding capacity (enables miniaturization and high-throughput processes)
- High functional group density of 3500 µmoles.g-1 vs 300-600 µmoles.g-1 for competitor technologies, allows for multi-point covalent attachment of bioseparation ligand reducing leaching and enhancing stability.
- Improved biomolecule purity and recovery
Technical advantages of ReSyn for biomolecule immobilization:
- High protein binding capacity (>100% protein loading)
- Enhanced protein stability through multipoint attachment
- Demonstrated enzyme activity retention
- Co-immobilization of multiple enzymes
- Immobilization of multimeric enzymes
Advantages of ReSyn Products
Conventional microparticle technologies use solid or porous/cracked microparticles with binding of biological molecules limited to the surface, in which is a key factor constraining performance and the development of new applications for microparticle technologies and products. To eliminate that key constraint, ReSyn Biosciences has developed a novel (patented) microparticle technology platform, comprising a hyper-porous polymer matrix that allows penetration of biological and synthetic molecules throughout the volume of the microparticles. Based on their advancement of MagReSyn technology, ReSyn Magnetic Beads offer exceptionally high surface area for binding of molecules and allows performance that is orders of magnitude greater than alternate technologies. The binding capacity serves as a major performance contributor to the number of applications and versatility for end-user applications by and further enables miniaturization, increased sensitivity and reducing the cost of R&D.
Products
MagReSyn® Streptavidin MAX
MagReSyn® Streptavidin MAX
MagReSyn® Streptavidin MAX
Specifically engineered for custom applications where maximum binding of biotinylated molecules is required.
MagReSyn® Streptavidin
MagReSyn® Streptavidin MAX
MagReSyn® Streptavidin MAX
MagReSyn® Streptavidin microparticles contain covalently coupled streptavidin for the enrichment of biotinylated molecules.
MagReSyn® Protein A
MagReSyn® Streptavidin MAX
MagReSyn® Protein A MAX
MagReSyn® Protein A microspheres contain covalently coupled Protein A for highly specific single-step purification of immunoglobulin G (IgG) to >95% purity from whole serum samples.
MagReSyn® Protein A MAX
MagReSyn® Protein A MAX
MagReSyn® Protein A MAX
MagReSyn® Protein A MAX microspheres have been specially engineered for custom applications where maximum antibody binding is desired.
MagReSyn® Protein G
MagReSyn® Protein A MAX
MagReSyn® Protein G
MagReSyn® Protein G is a proprietary magnetic polymeric microsphere support that provides a simple and convenient method for highly specific capture of various immunoglobulins from biological samples.
MagReSyn® NTA
MagReSyn® Protein A MAX
MagReSyn® Protein G
MagReSyn® NTA microspheres consist of nitrilotriacetic acid (NTA) residues with a strong metal-chelating property.
MagReSyn® TIO2
MagReSyn® Ti-IMAC HP
MagReSyn® TIO2
MagReSyn® TiO2 microspheres have been engineered to achieve the ultimate specificity, outperforming competitor products, with excellent phosphopeptide recovery.If customers can’t find it, it doesn’t exist. Clearly list and describe the services you offer. Also, be sure to showcase a premium service.
MagReSyn® ZrO2
MagReSyn® Ti-IMAC HP
MagReSyn® TIO2
MagReSyn® ZrO2 microspheres may be used alone or in combination with MagReSyn TiO2 and/or MagReSyn Ti-IMAC microspheres to enrich diverse types of phosphopeptides for comprehensive phosphoproteomics analyses.
MagReSyn® Ti-IMAC HP
MagReSyn® Ti-IMAC HP
MagReSyn® Ti-IMAC HP
Magnetic microparticles with chelated Ti4+ metal ions for highly-specific phosphopeptide enrichment
MagReSyn® Ti-IMAC
MagReSyn® Zr-IMAC HP
MagReSyn® Ti-IMAC HP
MagReSyn® Ti-IMAC magnetic microspheres carry chelated Ti4+ metal ions for highly-specific phosphopeptide enrichment.
MagReSyn® Zr-IMAC HP
MagReSyn® Zr-IMAC HP
MagReSyn® Zr-IMAC HP
Magnetic microparticles with chelated Zr4+ metal ions for highly-specific phosphopeptide enrichment.
MagReSyn® Zr-IMAC
MagReSyn® Zr-IMAC HP
MagReSyn® Zr-IMAC HP
MagReSyn® Zr-IMAC magnetic microspheres carry chelated Zr4+ metal ions for highly-specific phosphopeptide enrichment.
MagReSyn® Amine
MagReSyn® Carboxyl
MagReSyn® Carboxyl
MagResyn® Amine (NH2) functional microspheres may be used to physically adsorb biomolecules through ionic interaction, or they can be chemically functionalized for covalent coupling of biomolecules using a variety of bi-functional chemical coupling agents.
MagReSyn® Carboxyl
MagReSyn® Carboxyl
MagReSyn® Carboxyl
MagReSyn® Carboxyl is a magnetic polymeric microsphere support designed for covalent immobilization of primary amine-containing ligands through carbodiimide-succinimidyl ester activation and subsequent amide bond formation.
MagReSyn® SAX
MagReSyn® Carboxyl
MagReSyn® Trypsin
MagReSyn® SAX (strong anion exchanger) is a magnetic polymeric microsphere support designed for capture, purification and recovery of biomolecules such as proteins/peptides, enzymes, antibodies by exploiting differences in net charge to reversibly adsorb oppositely-charged molecules.
MagReSyn® Trypsin
MagReSyn® Chymotrypsin
MagReSyn® Trypsin
MagReSyn® Trypsin microspheres consist of covalently immobilized sequencing grade trypsin (TPCK treated to prevent chymotryptic activity) for protein digestion prior to mass spectrometry analysis.
MagReSyn® Chymotrypsin
MagReSyn® Chymotrypsin
MagReSyn® Chymotrypsin
MagReSyn® Chymotrypsin microspheres consist of covalently immobilized sequencing grade chymotrypsin (TLCK treated to prevent tryptic activity) for protein digestion prior to mass spectrometry analysis.
MagReSyn® HILIC
MagReSyn® Chymotrypsin
MagReSyn® Chymotrypsin
MagReSyn® HILIC provides a highly reproducible and fully automatable solution for parallel protein sample clean-up prior to MS analysis.
MagReSyn® Hydroxyl
MagReSyn® Hydroxyl
MagReSyn® Hydroxyl
MagReSyn® Hydroxyl, consists of hydroxyl terminated magnetic beads. The hydrophilic surface and neutral functionality reduces non-specific interactions, increasing recovery of peptides in for instance applications requiring on-bead digestion.
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Method Library
This resource aims to make methods more accessible to researchers, and help identify the most relevant workflows for your current application.